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FOXO4-DRI (10mg)

FOXO4-DRI (10mg)

$160.00

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FOXO4-DRI is a synthetic peptide designed to selectively target and eliminate senescent (aged) cells while protecting healthy cells. By interfering with the interaction between the FOXO4 protein and p53, it triggers apoptosis (programmed cell death) in damaged or non-functioning cells. This process, known as senolytic activity, helps the body clear cellular waste and promote regeneration. FOXO4-DRI has gained attention for its potential anti-aging, tissue repair, and longevity-enhancing properties, as well as its role in improving energy, resilience, and overall cellular health.
Generic Name:

FOXO4-DRI

Compound Information:

Molecular Weight: 2634.03 g/mol
Formula: C128H215N41O40
Anabolic Rating: N/A
Androgenic Rating: N/A

 

HOW MUCH YOU’LL NEED

SUGGESTED ORDER AMOUNT

As FOXO4-DRI is used in short blast protocols of 3–5 doses, one 10mg vial is typically sufficient for a single clearance cycle at the standard dose. A common approach is 2–3 vials per person per year, aligned with the recommended 3–6 month interval between blast protocols.

Dosage (Male)

10–20 mg per week

Dosage (Female)

10–20 mg per week

Dosage Frequency

2–3 times per week

Dosage Type

Subcutaneous Injection

MIXING & Usage Guidelines

01

Draw 1.0 mL of Bacteriostatic Water USP from the vial.

02

Carefully inject the Bacteriostatic Water into the FOXO4-DRI vial, aiming the stream along the side of the vial and avoiding direct contact with the lyophilized powder.

03

Gently swirl the vial until the powder is fully dissolved and the solution becomes clear. Do not shake the vial vigorously.

04

Once mixed, the concentration will be 10mg per mL (10mg per 1mL vial), equating to 1mg per 10 units on a standard insulin syringe. Remember, 100 units on the syringe equals 1mL, corresponding to the full 10mg dose.

05

The prepared solution can be administered subcutaneously (SubQ) in the lower abdominal fat area.

06

Once reconstituted with Bacteriostatic Water, the solution should be stored in the refrigerator. Use within 60 days to ensure potency and effectiveness.

WHEN TO TAKE it

FOXO4-DRI is typically administered in a pulsed protocol rather than daily, as it is a potent senolytic targeting accumulated senescent (“zombie”) cells. Most protocols suggest morning administration to allow the body to manage the cellular clearance process throughout the day.

Hydration is essential when using this peptide. On dosing days, significantly increasing water intake and adding a high-quality electrolyte helps support kidney filtration and reduce fatigue as the body processes cleared cellular debris.

Mild flu-like symptoms, lethargy, or joint achiness for 24–48 hours after dosing is a normal sign of detoxification as the body clears senescent cells. Increasing water intake and prioritising sleep during this window will help the body process and recover effectively.

RECOMMENDED SCHEDULE

  • Low Dose (1mg — 10 units): Ideal for a gentle introduction to senolytic therapy or longer maintenance pulses
  • Standard Dose (2mg — 20 units): The most common research dose for effective cellular cleanup without excessive detox stress
  • Advanced Dose (5mg — 50 units): For intensive protocols only — assess tolerance at lower doses before advancing
  • Clearance Schedule: Every other day for 3–5 doses (e.g., Monday, Wednesday, Friday)
  • Frequency: This blast protocol should only be performed once every 3–6 months

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Consult With a Healthcare Provider

Before considering the use of peptides, it’s important to speak with a licensed medical professional. They can assess your overall health, explain the potential benefits and risks, and provide tailored advice that fits your personal goals and medical history.

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Choose Reputable, Quality Sources

To minimize the risk of contaminated or counterfeit products, source peptides from reputable vendors like Pacific Peptides. Choose trusted suppliers with strict quality standards and a proven track record in the fitness or medical community. You can also check out reviews from our trusted customers to make an informed decision.

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Begin
Conservatively

When starting peptides, begin with the lowest dose that may offer results. Increase gradually only if necessary, paying close attention to how your body responds and watching for any unwanted effects along the way.

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PRIORITISE RECOVERY & MONITORING

Peptide protocols should be supported by proper recovery and regular self monitoring. Prioritizing sleep, nutrition, hydration, and stress management helps maximize results while reducing the risk of unwanted effects. Allowing adequate time between cycles supports long term metabolic health and overall well being.

Dosage (Male)

10–20 mg per week

Dosage (Female)

10–20 mg per week

Dosage Frequency

2–3 times per week

Dosage Type

Subcutaneous Injection

Active Half-Life

24 hours

Chemical Name

D-Retro-Inverso FOXO4 Peptide

Stack With...

NAD+, MOTs-C

Post-Cycle Therapy

N/A

Our Vision

10+ Years of Peptide Expertise

At Pacific Peptides our mission is to offer you access to the highest quality peptides, helping you achieve the physique and fitness goals you’ve always dreamed of. Each of our peptides is designed to enhance overall well-being, boost performance, and promote vitality. With over ten years of experience in peptide formulation, Pacific Peptides offers a wide range of products to help you reach your full potential.

 

Incorporate FOXO4-DRI Into a Stack

FOXO4-DRI is often combined with NAD+ or MOTs-C to maximize cellular rejuvenation and energy restoration. While FOXO4-DRI clears senescent cells and promotes regeneration, NAD+ replenishes cellular energy and supports DNA repair, and MOT-C enhances metabolic efficiency. Together, this combination forms a synergistic anti-aging protocol that supports energy, vitality, and longevity from the cellular level.

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Safe Disposale of Needle Tips and Syringes

Ensuring the proper disposal of utilized syringes and needles is crucial for the safety of yourself and those around you. Once used, promptly deposit the syringe and needle into a designated sharps container. Avoid recapping the needle to prevent unintentional needle pricks. Familiarize yourself with the regulations in your local area concerning the appropriate disposal of medical waste. Numerous regions have specific guidelines for discarding sharps containers, and adhering to them is vital to safeguard both your community and the environment.

Side Effects + Considerations

FOXO4-DRI is generally well tolerated, though mild fatigue, headache, or temporary nausea may occur after administration. Because it promotes the removal of senescent cells, some individuals may experience short-term detox-like effects such as muscle soreness or mild flu-like symptoms as the body clears damaged tissue. These effects are typically brief and signal the peptide’s regenerative activity. Maintaining hydration and rest during cycles can help support optimal recovery.
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